Cation Exchange Protocol to Radiolabel Rare-Earth Nanoparticles with Yttrium-90 for Radiotherapy and for Magnetic Resonance Imaging 来源:ACS PublicationsInternal radiation therapy (iRT) is an emerging therapeutic approach based on high-energy radionuclide implants categorized as alpha or beta particles placed directly into the tumor to induce cancer cell damage. This work focuses on the development of a unique approach for incorporating β-emitter yttrium-90 (90Y) radionuclides via a cation exchange method into lanthanide-based nanoparticles (NPs), consisting of NaLnF4 composition (Ln = Gd, ...
Release time:
2025
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12
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来源:ACS PublicationsA series of vanadium-doped orthoniobates of the type La(Nb1–xVx)O4 (x = 0.00–0.40) were synthesized using a solid-state method, and their long-range average and short-range local structures comprehensively investigated using a combination of high-resolution neutron powder diffraction (NPD) and synchrotron X-ray powder diffraction (S-XRD) that produced accurate and precise structures of several members of the series. The structures evolve from a monoclinic fergusonite-type to a tetragonal scheelite-type structure as the V content increases. Substituting Nb5+ by the smaller V5...
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2025
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06
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Synergistic Effects of Multimodal Polydopamine Coating on NaGdF4@NaYF4:Nd3+ Nanostructured Alginate Microspheres through the Combination of Chemotherapy and Photothermal Therapy 来源:ACS PublicationsNanophosphors have gained substantial attention in recent years for both the diagnosis and treatment of cancer. Near-infrared optical imaging based on Nd3+-doped rare-earth nanophosphors is widely used for deep penetration tissue imaging. The present work aims to develop a hierarchical structure of polydopamine (PDA)-coated alginate microspheres encapsulated with NaGdF4@NaYF4:Nd3+ and cisplatin ...
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2025
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Addressing Discrepancies between Theory and Experiments in Boltzmann Luminescence Thermometry with Ln3+ Ions 来源:ACS PublicationsTrivalent lanthanide ion-doped nanoparticles are widely employed as nanoscale thermometers, driving rapid advancements in real-world applications. When using the Luminescence Intensity Ratio (LIR) technique, a calibration process is often required to determine macroscopic calibration parameters. However, despite extensive studies from various research groups, significant discrepancies are observed among the reported values, even for identical Ln3+–host systems un...
Release time:
2025
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09
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